Investigation of the Levels of Some Antioxidant and Inflammatory Markers Following Supplementation of CoenzymeQ10 after Acute Bouts of Exhausting Aerobic Exercise in Male Judo Athletes

Document Type : Original Article

Authors

1 PhD student in Exercise Physiology, Department of Kinesiology and Sport Management, Texas A&M University, Texas, USA.

2 Masters student, Department of Exercise Physiology, Faculty of Humanities and Social Sciences, University of Kurdistan, Sanandaj, Iran.

3 Postdoctoral researcher, Department of Exercise Physiology, Faculty of Humanities and Social Sciences, University of Kurdistan, Sanandaj, Iran.

Abstract

Aim: This study aimed to investigate the effects of short-term supplementation with coenzyme Q10 (CoQ10) on markers of oxidative stress and inflammation, specifically superoxide dismutase (SOD), malondialdehyde (MDA), and interleukin-6 (IL-6), following exhaustive aerobic exercise in judo athletes.

Method: Sixteen male judo athletes participated in a randomized, double-blind, crossover study in which they received CoQ10 or placebo. Participants received CoQ10 supplementation for 30 days after completing a first bout of exhaustive aerobic exercise, then completed a second bout of exhaustive exercise. Blood samples were collected before exercise, immediately, and 24 hours after exercise during the two bouts to measure levels of SOD, MDA, and IL-6. These markers were analyzed using enzyme-linked immunosorbent assay (ELISA) and spectrophotometric techniques.

Results: CoQ10 supplementation significantly increased SOD levels after 30 days of supplementation compared to the placebo group (p<0.05). MDA and IL-6 levels were significantly reduced during the recovery period after CoQ10 supplementation (p<0.05). These findings suggest that CoQ10 effectively enhances antioxidant defences and reduces lipid peroxidation and inflammation induced by exhaustive aerobic exercise.

Conclusion: CoQ10 supplementation improves oxidative stress and inflammatory responses in judo athletes after exhaustive aerobic exercise. CoQ10 may be an effective nutritional strategy to enhance recovery and reduce exercise-induced cellular damage in high-intensity sports

Keywords

Main Subjects

References

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Research in Exercise Nutrition
Volume 2, Issue 4 - Serial Number 4
February 2024
Pages 61-68

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History

  • Receive Date: 03 December 2024
  • Revise Date: 21 December 2024
  • Accept Date: 23 December 2024
  • First Publish Date: 23 December 2024

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