Comparing the effects of creatine malate, betaine and beta-alanine supplements on the performance of boxing athletes

Document Type : Original Article

Authors

Department of Exercise Physiology, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran.

Abstract

Aim: The purpose of the present study was to compare the effect of creatine malate, betaine and beta-alanine supplements on the performance of boxing athletes.
Method: First, dependent variables were measured in 15 boxing athletes and from the next day they consumed the first supplement for ten days. Then a wash-out period was considered for two weeks, after that the subjects consumed the second supplement for ten days. Another two-weeks was considered for wash-out and after that the subjects consumed the third supplement for ten days. Dependent variables were measured after the end of each supplement period. The order of taking the supplements was chosen randomly.
Results: One maximum repetition of squat and bench press following creatine malate intake were significantly higher compared to betaine (p<0.001, p<0.005 respectively) and control (both p<0.001) and following beta-alanine intake compared to betaine (p<0.007, p<0.017 respectively) and control (p<0.005, p<0.014 respectively). The duration of agility following beta-alanine consumption was significantly lower compared to creatine malate (p<0.015), betaine (p<0.001) and control (p<0.001). The reaction speed following beta-alanine consumption was significantly higher compared to creatine malate (p<0.016), betaine (p<0.023) and control (p<0.001).
Conclusion: The results of this research showed that the consumption of creatine malate is more effective in improving muscle strength and the consumption of beta-alanine is more effective in improving agility and reaction speed, and the consumption of betaine does not have a significant effect on the performance of boxing athletes.

Keywords

Main Subjects


  1. Bonilla DA, Boullosa D, Del Coso J. Advances in Nutrition, Dietary Supplements and Ergogenic Aids for Athletic Performance: Trends and Future Prospects. Nutrients. 2023; 15(10):2246.
  2. Greer, B.K., The effects of branched-Chain amino acid supplementation on indirect indicators of muscle damage and performance. 2006.
  3. Harty PS, Cottet ML, Malloy JK, Kerksick CM. Nutritional and Supplementation Strategies to Prevent and Attenuate Exercise-Induced Muscle Damage: a Brief Review. Sports Med Open. 2019 Jan 7;5(1):1.
  4. Adamczyk, J. G. "Support Your Recovery Needs (SYRN) - a Systemic Approach to Improve Sport Performance." Biomedical Human Kinetics. 2023 15 (1): 269-279.
  5. Wax B, Kerksick CM, Jagim AR, Mayo JJ, Lyons BC, Kreider RB. Creatine for Exercise and Sports Performance, with Recovery Considerations for Healthy Populations. Nutrients. 2021 Jun 2;13(6):1915.
  6. Tiidus, P.M., Skeletal muscle damage and repair. 2008: Human Kinetics.
  7. Cooke, M.B., et al., Creatine supplementation enhances muscle force recovery after eccentrically-induced muscle damage in healthy individuals. Journal of the International Society of Sports Nutrition, 2009. 6(1): p. 13.
  8. Parthasarathy A, Savka MA, Hudson AO. The Synthesis and Role of β-Alanine in Plants. Front Plant Sci. 2019 Jul 18;10:921.
  9. Harris, R.C., et al., The absorption of orally supplied β-alanine and its effect on muscle carnosine synthesis in human vastus lateralis. Amino acids, 2006. 30(3): p. 279-289.
  10. Blancquaert L, Everaert I, Derave W. Beta-alanine supplementation, muscle carnosine and exercise performance. Curr Opin Clin Nutr Metab Care. 2015 Jan;18(1):63-70.
  11. Suzuki, Y., et al., High level of skeletal muscle carnosine contributes to the latter half of exercise performance during 30-s maximal cycle ergometer sprinting. The Japanese journal of physiology, 2002. 52(2): p. 199-205.
  12. Saunders, B., et al., β-alanine supplementation to improve exercise capacity and performance: a systematic review and meta-analysis. British Journal of Sports Medicine, 2017. 51(8): p. 658-669.
  13. Craig, S.A., Betaine in human nutrition. The American journal of clinical nutrition, 2004. 80(3): p. 539-549
  14. Willingham BD, Ragland TJ, Ormsbee MJ. Betaine Supplementation May Improve Heat Tolerance: Potential Mechanisms in Humans. Nutrients. 2020 Sep 25;12(10):2939.
  15. Trepanowski, J.F., et al., The effects of chronic betaine supplementation on exercise performance, skeletal muscle oxygen saturation and associated biochemical parameters in resistance trained men. The Journal of Strength & Conditioning Research, 2011. 25(12): p. 3461-3471.
  16. Hoffman, J.R., et al., Effect of betaine supplementation on power performance and fatigue. Journal of the International Society of Sports Nutrition, 2009. 6(1): p. 7
  17. Hoffman, J.R., et al., Effect of 15 days of betaine ingestion on concentric and eccentric force outputs during isokinetic exercise. The Journal of Strength & Conditioning Research, 2011, 25 (8): p. 2235-2241.
  18. Lee, E.C., et al., Ergogenic effects of betaine supplementation on strength and power performance. Journal of the International Society of Sports Nutrition, 2010. 7(1): p. 27.
  19. Fernández-Lázaro D, Fiandor EM, García JF, Busto N, Santamaría-Peláez M, Gutiérrez-Abejón E, Roche E, Mielgo-Ayuso J. β-Alanine Supplementation in Combat Sports: Evaluation of Sports Performance, Perception, and Anthropometric Parameters and Biochemical Markers-A Systematic Review of Clinical Trials. Nutrients. 2023 Aug 28;15(17):3755 
  20. Durkalec-Michalski K, Kusy K, Ciekot-Sołtysiak M, Zieliński J. The Effect of Beta-Alanine versus Alkaline Agent Supplementation Combined with Branched-Chain Amino Acids and Creatine Malate in Highly-Trained Sprinters and Endurance Athletes: A Randomized Double-Blind Crossover Study. Nutrients. 2019 Aug 21;11(9):1961
  21. Pryor JL, Craig SA, Swensen T. Effect of betaine supplementation on cycling sprint performance. J Int Soc Sports Nutr. 2012 Apr 3;9(1):12. 
  22. Siahkouhian, M., Afroundeh, R. (2009). Principles of physical fitness testing (coaching guide). 1th Edition. Sanaye Sorkh.
  23. Maicas-Pérez L, Hernández-Lougedo J, Heredia-Elvar JR, Pedauyé-Rueda B, Cañuelo-Márquez AM, Barba-Ruiz M, Lozano-Estevan MDC, García-Fernández P, Maté-Muñoz JL. Effects of Creatine Supplementation after 20 Minutes of Recovery in a Bench Press Exercise Protocol in Moderately Physically Trained Men. Nutrients. 2023 Jan 28;15(3):657.
  24. Wang, C.-C., et al., Effects of creatine supplementation on muscle strength and optimal individual post-activation potentiation time of the upper body in canoeists. Nutrients, 2017. 9(11): p. 1169.
  25. Sterkowicz, S., et al., The effects of training and creatine malate supplementation during preparation period on physical capacity and special fitness in judo contestants. Journal of the International Society of Sports Nutrition, 2012. 9(1): p. 41.
  26. Wan JJ, Qin Z, Wang PY, Sun Y, Liu X. Muscle fatigue: general understanding and treatment. Exp Mol Med. 2017 Oct 6;49(10):e384. doi: 10.1038/emm.2017.194. PMID: 28983090; PMCID: PMC5668469.
  27. Baguet, A., et al., β-Alanine supplementation reduces acidosis but not oxygen uptake response during high-intensity cycling exercise. European journal of applied physiology, 2010. 108(3): p. 495-503.
  28. Blancquaert, L., et al., Effects of histidine and β-alanine supplementation on human muscle carnosine storage. Medicine & Science in Sports & Exercise, 2017. 49(3): p. 602-609.
  29. Lamont, C. and D. Miller, Calcium sensitizing action of carnosine and other endogenous imidazoles in chemically skinned striated muscle. The Journal of Physiology, 1992. 454(1): p. 421-434.
  30. Jagim, A.R., et al., Effects of beta-alanine supplementation on sprint endurance. The Journal of Strength & Conditioning Research, 2013. 27(2): p. 526-532.
  31. Cholewa JM, Hudson A, Cicholski T, Cervenka A, Barreno K, Broom K, Barch M, Craig SAS. The effects of chronic betaine supplementation on body composition and performance in collegiate females: a double-blind, randomized, placebo controlled trial. J Int Soc Sports Nutr. 2018 Jul 31;15(1):37. 
  32. Cholewa, J.M., L. Guimaraes-Ferreira, and N.E. Zanchi, Effects of betaine on performance and body composition: a review of recent findings and potential mechanisms. Amino acids, 2014. 46(8): p. 1785-1793.
  33. Ostfeld I, Hoffman JR. The Effect of β-Alanine Supplementation on Performance, Cognitive Function and Resiliency in Soldiers. Nutrients. 2023 Feb 19;15(4):1039.
Volume 2, Issue 2
March 2024
Pages 46-37
  • Receive Date: 27 November 2023
  • Revise Date: 12 January 2024
  • Accept Date: 17 February 2024
  • First Publish Date: 17 February 2024