The effect of thyme supplementation along with exposure to hypoxia chamber on the glycemic indices in type 2 diabetic rats

Document Type : Original Article

Authors

1 Department of General Studies and intuition, Tabriz University of Islamic Arts, Tabriz, Iran.

2 Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tabriz, Tabriz, Iran.

Abstract

Aims: chronic hypoxia can control obesity-related diseases on the side of Thyme, due to its antioxidant properties due to phenyl compounds can increase the activity of mitochondrial oxidative enzymes and affect diabetic indicators. Therefore, the aim of the current research is to examine the impact of chronic hypoxia in supplementary Thymus, on diabetic indicators of type 2 diabetics in Rats.

Methods: In this study, Rats were randomly divided into 5 groups of 8: the first healthy control group (NC), the second diabetes group (D), the third diabetes + Thyme (D+Th), the fourth diabetes + chronic hypoxia (D + Al) and the fifth diabetes combination group (Al + D + Th).
Results: After 8 weeks, the glucose levels were 261.25±35.52 in the diabetic thyme group, 243.25±24.52 in the diabetes mellitus group, and 229.66±21.10 in the combination group, which analyzed the results of the ANOVA test showed that in the three groups, the level of ANOVA was significantly reduced after 8 weeks but had the most significant decrease in the thyme supplementation and hypoxia group (p<0.05). The insulin and insulin sensitivity index in the combined group also increased significantly in the diabetic control group, while hypoxia and Thyme did not have a significant effect.

Conclusion: it seems that the combination of Thyme supplementary and hypoxia contributes to the reduction of insulin resistance in improving diabetes indicators.

Keywords

Main Subjects


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Volume 2, Issue 2
March 2024
Pages 35-27
  • Receive Date: 26 November 2023
  • Revise Date: 19 December 2023
  • Accept Date: 17 February 2024
  • First Publish Date: 17 February 2024