بررسی اثر تعاملی یک دوره تمرینات ورزشی تناوبی با شدت بالا و مکمل سازی دارچین بر سطوح برخی نشانگرهای التهابی و ضد التهابی در مردان دارای اضافه وزن

نوع مقاله : مقاله اصیل

نویسندگان

1 گروه تربیت بدنی و علوم ورزشی، واحد علوم و تحقیقات ، دانشگاه آزاد اسلامی، تهران، ایران.

2 گروه تربیت بدنی و علوم ورزشی. دانشکده علوم ورزشی دانشگاه آزاد اسلامی واحد اراک، ایران

3 گروه تربیت بدنی و علوم ورزشی، دانشگاه آزاد اسلامی واحد علوم و تحقیقات، تهران، ایران.

4 گروه تربیت بدنی و علوم ورزشی، دانشکده علوم ورزشی، دانشگاه آزاد اسلامی، واحد تهران مرکز، تهران، ایران.

5 گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی،دانشگاه آزاد اسلامی واحد تهران مرکز، تهران، ایران.

10.34785/J019.2023.004

چکیده

مقدمه: پژوهش حاضر با هدف بررسی اثر تعاملی یک دوره تمرینات تناوبی با شدت بالا و مکمل سازی دارچین بر سطوح برخی نشانگرهای ضد التهابی در مردان دارای اضافه وزن و چاق انجام گردید.
روش شناسی: 40 مرد بزرگسال چاق و دارای اضافه وزن با شاخص توده بدنی بیشتر از 26 کیلوگرم/ مجذور قد به متر بصورت تصادفی به 4 گروه 1) مکمل دارچین، 2) تمرینات HIIT، 3) مکمل + تمرینات HIIT و 4) پلاسیبو تقسیم بندی شدند. سپس آزمودنی ها به مدت 8 هفته تحت مداخله های مختلف مکمل دارچین و تمرینات HIIT قرار گرفتند. شاخص های آنتروپومتریکی و التهابی و ضد التهابی در دو مرحله پیش آزمون- پس آزمون اندازه گیری شد.
نتایج: نتایج تحلیل داده ها نشان داد که سطوح سرمی IL-6 و TNFa و شاخص مقاومت به انسولین در گروه های مکمل، تمرینات HIIT و مکمل+ تمرینات HIIT در پس آزمون نسبت به پیش آزمون کاهش معناداری داشت (05/0 ≥ P)، در حالی که سطوح سرمی آدیپونکتین در گروه های مکمل، تمرینات HIIT و مکمل+ تمرینات HIIT افزایش معناداری در پس آزمون داشت (05/0 ≥ P). این در حالی است که در هیچ کدام از متغیرها تفاوت معناداری بین گروه ها وجود نداشت (05/0 ≤ P).
نتیجه گیری: با توجه به نتایج بدست آمده می توان گفت که اجرای تمرینات HIIT با و بدون مکمل سازی دارچین احتمالا از طریق کاهش سطوح نشانگر های التهابی و افزایش نشانگر های ضد التهابی باعث بهبود مقاومت به انسولین در مردان چاق دارای اضافه وزن می گردد.

کلیدواژه‌ها

موضوعات


عنوان مقاله [English]

Interactive effect of a period of high-intensity interval training and cinnamon supplementation on the levels of some inflammatory and anti-inflammatory markers in overweight men

نویسندگان [English]

  • Hadis Bayat 1
  • Hamidreza Khalounejad 2
  • Masoud Babaei 3
  • Nazanin Arnavazi yamchi 4
  • Mohammad Ali Azarbayjani 5
1 Department of Physical Education and Sports Sciences, Science and Research Unit, Islamic Azad University, Tehran, Iran.
2 Department of Physical Education and Sports Science. Faculty of Sports Sciences, Islamic Azad University Arak Branch, Iran
3 Department of Physical Education and Sports Sciences, Islamic Azad University, Department of Science and Research, Tehran, Iran.
4 Department of Physical Education and Sports Sciences, Faculty of Sports Sciences, Islamic Azad University, Tehran Branch, Center, Tehran, Iran.
5 Exercise Physiology Departments, Faculty of Physical Education, Islamic Azad University, Central Tehran Branch, Iran
چکیده [English]

Introduction: The aim of this study was to investigate the interactive effect of a period of high-intensity interval training and cinnamon supplementation on the levels of some inflammation and anti-inflammatory markers in overweight and obese men.
Methodology: 40 obese and overweight adult men with body mass index greater than 26 kg / m2 were randomly divided into 4 groups: 1) Cinnamon supplement, 2) HIIT training, 3) HIIT supplement + HIIT training, and 4) placebo Were classified. Subjects were then subjected to various cinnamon supplement interventions and HIIT exercises for 8 weeks. Anthropometric, inflammatory and anti-inflammatory indices were measured in two stages: pre-test and post-test.
Results: The results of data analysis showed that serum levels of IL-6 and TNFα and insulin resistance index in the complementary groups, HIIT training and supplement + HIIT training in the post-test were significantly reduced compared to the pre-test (P ≤ 0.05). While serum adiponectin levels in supplement groups, HIIT training and supplement + HIIT training had a significant increase in post-test (P ≤ 0.05). However, there was no significant difference between the groups in any of the variables (P ≥ 0.05).
Conclusion: According to the results, it can be said that performing HIIT training with and without cinnamon supplementation will probably improve insulin resistance in overweight men by reducing the levels of inflammatory markers and increasing anti-inflammatory markers.

کلیدواژه‌ها [English]

  • High Intensity Interval training
  • Adiponectin
  • Inflammation and Obesity
  1. Gholaman M, Gholami M, Azarbayjani MA, Abed Natanzi H. High and Moderate Intensity Aerobic Training Effects on Galectin-3, Pentraxin-3, and Several Inflammatory Mediators Levels in Type 2 Diabetic Women, a Randomized Clinical Trial. Women’s Health Bulletin. 2021;8(4):238-46.
  2. Raman A. The role of exercise in glycaemic control and inflammation in overweight/obese individuals with and without type 2 diabetes: Murdoch University; 2018.
  3. Torres-García R, del Socorro Camarillo-Romero E, Majluf-Cruz A, de Anda GFV, Loe-Ochoa AM, Montenegro-Morales LP, et al. Effect of exercise on the serum concentrations of leptin and adiponectin in adolescents with risk factors of developing diabetes. Revista medica del instituto mexicano del seguro social. 2018;55(6):708-14.
  4. Tsiotra PC, Halvatsiotis P, Patsouras K, Maratou E, Salamalekis G, Raptis SA, et al. Circulating adipokines and mRNA expression in adipose tissue and the placenta in women with gestational diabetes mellitus. Peptides. 2018;101:157-66.
  5. میر, فتحی. تغییرات ویسفاتین پلاسما و مقاومت به انسولین در زنان چاق مبتلا به دیابت نوع 2 پس از تمرینات پیلاتس. مجله سلامت و مراقبت.20(1):30-9.
  6. Roque FR, Hernanz R, Salaices M, Briones AM. Exercise training and cardiometabolic diseases: focus on the vascular system. Current hypertension reports. 2013;15(3):204-14.
  7. Safdar A, Saleem A, Tarnopolsky MA. The potential of endurance exercise-derived exosomes to treat metabolic diseases. Nature Reviews Endocrinology. 2016;12(9):504-17.
  8. Goodpaster BH, Sparks LM. Metabolic flexibility in health and disease. Cell metabolism. 2017;25(5):1027-36.
  9. Gruenwald J, Freder J, Armbruester N. Cinnamon and health. Critical reviews in food science and nutrition. 2010;50(9):822-34.
  10. Leach MJ, Kumar S. Cinnamon for diabetes Cochrane database of systematic reviews. 2012(9).
  11. Castro CAd, Silva KAd, Rocha MC, Sene-Fiorese M, Nonaka KO, Malavazi I, et al. Exercise and omentin: their role in the crosstalk between muscle and adipose tissues in type 2 diabetes mellitus rat models. Frontiers in physiology. 2019:1881.
  12. Nassis GP, Papantakou K, Skenderi K, Triandafillopoulou M, Kavouras SA, Yannakoulia M, et al. Aerobic exercise training improves insulin sensitivity without changes in body weight, body fat, adiponectin, and inflammatory markers in overweight and obese girls. Metabolism. 2005;54(11):1472-9.
  13. Sirico F, Bianco A, D'Alicandro G, Castaldo C, Montagnani S, Spera R, et al. Effects of physical exercise on adiponectin, leptin, and inflammatory markers in childhood obesity: systematic review and meta-analysis. Childhood Obesity. 2018;14(4):207-17.
  14. Achari AE, Jain SK. Adiponectin, a therapeutic target for obesity, diabetes, and endothelial dysfunction. International journal of molecular sciences. 2017;18(6):1321.
  15. Madsen SM, Thorup AC, Overgaard K, Jeppesen PB. High intensity interval training improves glycaemic control and pancreatic β cell function of type 2 diabetes patients. PloS one. 2015;10(8):e0133286.
  16. Asle Mohammadi Zadeh M, Kargarfard M, Marandi SM, Habibi A. Diets along with interval training regimes improves inflammatory & anti-inflammatory condition in obesity with type 2 diabetes subjects. Journal of Diabetes & Metabolic Disorders. 2018;17(2):253-67.
  17. Kazemi A, Rahmati M, Akhondi M. Effect of 6 weeks of high-intensity interval training with cinnamon supplementation on serum apelin concentration and insulin resistance in overweight boys. The Horizon of Medical Sciences. 2016;22(3):177-83.
  18. Baigzadeh M, Delavar SH, Safikhani H. The Effect of Training (Aerobic and Concurrent) and Cinnamon Supplementation on the Plasma Levels of Visfatin and Adiponectin in Overweight Diabetic Men. Journal of Clinical Research in Paramedical Sciences. 2020;9(2).
  19. Rashidlamir A, Alizadeh A, Ebrahimiatri A, Dastani M. The effect of four-week period of aerobic exercise with cinnamon consumption on lipoprotein indicates and blood sugar in diabetic female patients (type 2). SSU_Journals. 2013;20(5):605-14.
  20. Clark T, Morey R, Jones MD, Marcos L, Ristov M, Ram A, et al. High-intensity interval training for reducing blood pressure: a randomized trial vs. moderate-intensity continuous training in males with overweight or obesity. Hypertension Research. 2020;43(5):396-403.
  21. Steckling FM, Farinha JB, Figueiredo FdC, Santos DLD, Bresciani G, Kretzmann NA, et al. High-intensity interval training improves inflammatory and adipokine profiles in postmenopausal women with metabolic syndrome. Archives of physiology and biochemistry. 2019;125(1):85-91.
  22. Banitalebi E, Kazemi A, Faramarzi M, Nasiri S, Haghighi MM. Effects of sprint interval or combined aerobic and resistance training on myokines in overweight women with type 2 diabetes: A randomized controlled trial. Life sciences. 2019;217:101-9.
  23. Robinson E, Durrer C, Simtchouk S, Jung ME, Bourne JE, Voth E, Little JP. Short-term high-intensity interval and moderate-intensity continuous training reduce leukocyte TLR4 in inactive adults at elevated risk of type 2 diabetes. Journal of applied physiology. 2015;119(5):508-16.
  24. Alizadeh Pahlavani H. Exercise Therapy for People With Sarcopenic Obesity: Myokines and Adipokines as Effective Actors. Frontiers in Endocrinology. 2022;13.
  25. Pedersen B, Steensberg A, Fischer C, Keller C, Keller P, Plomgaard P, et Searching for the exercise factor: is IL-6 a candidate? Journal of Muscle Research & Cell Motility. 2003;24(2):113-9.
  26. Weston KS, Wisløff U, Coombes JS. High-intensity interval training in patients with lifestyle-induced cardiometabolic disease: a systematic review and meta-analysis. British journal of sports medicine. 2014;48(16):1227-34.
  27. Little JP, Jung ME, Wright AE, Wright W, Manders RJ. Effects of high-intensity interval exercise versus continuous moderate-intensity exercise on postprandial glycemic control assessed by continuous glucose monitoring in obese adults. Applied physiology, nutrition, and metabolism. 2014;39(7):835-41.
  28. Tjønna AE, Lee SJ, Rognmo Ø, Stølen TO, Bye A, Haram PM, et al. Aerobic interval training versus continuous moderate exercise as a treatment for the metabolic syndrome: a pilot study. Circulation. 2008;118(4):346-54.
  29. Fayaz E, Damirchi A, Zebardast N, Babaei P. Cinnamon extract combined with high-intensity endurance training alleviates metabolic syndrome via non-canonical WNT signaling. Nutrition. 2019;65:173-8.
  30. Tangvarasittichai S, Sanguanwong S, Sengsuk C, Tangvarasittichai O. Effect of cinnamon supplementation on oxidative stress, inflammation and insulin resistance in patients with type 2 diabetes mellitus. Int J Toxicol Pharmacol Res. 2015;7(4):56-9.
  31. Tian HW, Shen HY, Zhang XG, Li X, Jiang WX, Cui TJ. Terahertz metasurfaces: toward multifunctional and programmable wave manipulation. Frontiers in Physics. 2020;8:448.

 

دوره 1، شماره 2
شهریور 1401
صفحه 35-42
  • تاریخ دریافت: 25 خرداد 1401
  • تاریخ بازنگری: 16 شهریور 1401
  • تاریخ پذیرش: 19 آبان 1401
  • تاریخ اولین انتشار: 19 آبان 1401